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Andreeff, M, Tsao T, Lapillonne H, Sudarikov A, McQueen T, Hu W, Monaco G, R-Y W, Belmont J, Sporn M, Konopleva M

To investigate whether the differences in the concentration of total soluble protein and the yields were statistically significant for the different combinatorial strategies of purification, One-way ANOVA was performed with Tuckeys method that uses studentized range distribution [36]

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Its to name the genuinely safer path and be honest that even the safer path doesnt turn an unproven compound into a proven one