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-Secretase has been characterized as a membrane-bound aspartic protease termed beta-site APP-cleaving enzyme 1 (BACE1), while -secretase is a complex comprised of presenilin-1 or -2, nicastrin, anterior pharynx-defective 1 (Aph-1) and presenilin enhancer 2 (Pen-2

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Its really about local control, Rein said, because there are other landowners in the southern High Plains that may want to continue to have that right to appropriate water. But when local wells go dry, people migrate from the area to larger towns and cities, McKinley said

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