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et al., 2021), ALS (Yu et al., 2020), multiple sclerosis (Woo et al., 2024), and neovascular age-related macular degeneration (Tanaka et al., 2024)

Therefore, appropriate doses of these agents are expected to alleviate ferroptosis in CNS diseases through the Nrf2 and vitagenes pathways (Table 1)

BJP-IVb reduces iron content to prevent PD by inhibiting iron regulatory protein in dopaminergic neurons

Frontiers in Pharmacology , 12, 627533

Lee HJ, Meinardi S, Pahl MV, Vaziri ND, Blake DR

Adventitial injection of HA/SA hydrogel loaded with PLGA rapamycin nanoparticle inhibits neointimal hyperplasia in a rat aortic wire injury model