(2000) additionally revealed that only 4452% of the radioactivity excreted in urine came from unmodified OTA, clearly indicating the formation of phase 1 or phase 2 metabolites
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For example, injectable pyridoxine solutions may contain aluminum as a trace impurity, and with prolonged use in patients with renal impairment (especially premature neonates with immature kidneys) there is a risk of aluminum accumulation and toxicity
Cell & bioscience, 13(1), 81
V., Madhan, B., Glattauer, V., & Ramshaw, J
Nasiri-Amiri et al., 2023)