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In addition, how the supplementation dose of small molecular antioxidants affects their intracellular levels and whether radical scavenging activity at the site of action is feasible are unknown

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and decreased mitochondrial aconitase activity and mitochondrial membrane potential are observed in HepG2 lines overexpressing CYP2E1 in mitochondria (mE10 and mE27 cells) treated with BSO as compared with cells transfected with empty vector (pCI-neo) [5]

This study demonstrated a more focused and efficient technique to provide a fresh perspective on quercetin treatment for AD processes [110]

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doi: 10.3389/fgene.2015.00148