Several birds with one stone: exploring the potential of AI methods for multi-target drug design
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2.4.4 The association between microplastics and central nervous system neoplasms Toxicological testing and metabolic profiling results demonstrate that nano/micron polystyrene materials (n/mPS) exert significant toxic effects on SH-SY5Y human neuroblastoma cells, with enhanced toxicity under oxidative conditions ultimately leading to cytotoxicity and metabolic disturbances (59), revealing microplastics intervention in tumor cells
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Effective drugs need to interfere with this replication process, shutting down the viruss ability to proliferate inside the host, said Hussin Rothan, a post-doctoral researcher at Georgia State and co-author of the study