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A transient breach in the epithelial barrier leads to regulatory T-cell generation and resistance to experimental colitis

Enhanced permeability of the BBB and subsequent leakage of blood contents exacerbate BBB disruption, fueling a vicious cycle detrimental to the imbalance of the CNS, ultimately contributing to neuronal degeneration, and driving neurodegenerative disorders pathophysiology

Cell 16 , 550561 (2005)

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BPC-157s origin in gastric juice allows it to remain stable and active in the acidic environment of the stomach

They make sense conceptually but need clinical trials to determine safety, dosage, timing and interactions