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Since both accumulation and complete elimination of BACE1/A adversely affect recovery after SCI, biological regulation of A or BACE1 levels after SCI by modulation of components of the UPS such as Fbx2-Uch-L1 via peroxisome proliferator-activated receptor-gamma co-activator (PGC)-1alpha or gene expression (Gong et al., 3)

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A genome-wide CRISPR screen identifies USP1 as a novel regulator of the mammalian circadian clock

doi: 10.7314/APJCP.2014.15.9.4019

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