Anyone taking methyl-donor-sensitive medications (some psychiatric drugs, methotrexate, methylated B-vitamin protocols at high doses): NNMT shares the methyl donor SAM, so theoretical interactions exist
Typically administered weekly, they can be given intramuscularly or subcutaneously
But interest isn't evidence
By being proactive about their nutrition, they can stay healthy, enjoy a good quality of life, and make the most of their weight loss
However, for individuals who require high doses or have difficulty absorbing the vitamin, injections may be a more practical option
A challenge with this vitamin is that some people can eat plenty of B12-rich foods but still can't absorb it properly