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Although reactive electrophiles such as chloroacetamides are generally considered to be promiscuous in target binding, we demonstrated here using a BODIPY-labelled analogue that the chloroacetamide-based GSTO1 inhibitor C1-27 exhibited a low degree of nonspecific reactivity

Several factors can cause glutathione deficiency, such as poor nutrition, exposure to environmental toxins, chronic stress, and the natural aging process

Frontiers Neurosci