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That is because the administration of ascorbate into a high oxidative stress environment increases tissue concentrations of glutathione, indicating that ascorbate (vitamin C) spares glutathione

1820 In conjunction with the use of these Sustainable Technology Division, National Risk Management Research Laboratory, U

Bozinovski S, Seow HJ, Crack PJ, Anderson GP, Vlahos R

Since APE1/Ref-1 expression represents a molecular marker of oxidative stress, it would be important to understand the dissection of signaling pathways responsible for its role in regulating the mechanisms of ROS-induced cell responses

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