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They are not large enough to draw conclusions about using it as a treatment, nor to prove that L-theanine works

IUPAC, Commission on Nomenclature of Organic Chemistry

Additionally, the enrichment of histone H3K4 trimethylation (H3K4me3) in the promoter region of METTL14 is significantly reduced in CRC cells, while KDM5C (Lysine Demethylase 5C)-mediated demethylation of H3K4me3 suppresses METTL14 transcription

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This can be achieved by incorporating negatively charged carboxyl groups into the NH 2 group of glucosamine units or C-6 hydroxyl groups (Yu and Li, 2023