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"Mr Farah understood the question one way and as soon as he left the room he asked Mr Fudge and immediately returned to clarify and it is plain the investigators were comfortable with this explanation," the letter read
Almaghamsi et al., 2021)
EMT is a critical biological process through which malignant tumor cells derived from epithelial cells acquire migratory and invasive capabilities
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The standout compound in the study, 34 , showed an IC 50 value of 91 nM for XO inhibition, compared to febuxostat which showed an IC 50 of 20 nM (Figure 12)