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The experimental design is summarized in Table 1

Our experimental protocol consisted in of stimulation of human ECs with recombinant SARS-CoV-2 spike protein, S1 subunit (rS1p) (accession number: QHD43416

Primary cells of the NVU may also be isolated in the laboratory (Bernas et al., via expression of the catalytic subunit of human telomerase (hTERT) and SV40 large T-antigen (Weksler et al., 2005)

Immune System Support Vitamin D is well-known for its role in enhancing immune system function, as it helps activate cells that combat infections and reduces inflammation

247,248 The key targets of the PI3K/AKT pathway and their related regulatory mechanisms are shown in Fig

Some studies have combined IGF-1 LR3 with PTH analogs or other bone-active compounds to study additive or synergistic effects on bone density and structure in rodent models