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The macrocycle 23 was selected as a proper research tool for more detailed studies since the molecule is convenient to prepare and due to its structural similarity to the IRAP substrates oxytocin and vasopressin in its N-terminal

Indeed, ALT telomeres have a relaxed telomeric chromatin configuration (compared to telomerase positive and normal cells) making them more susceptible to DNA damage and telomere elongation through ALT (Lin et al 2021

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Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

Pajouhesh, G.R