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These results imply that SFN increases protein oxidation in primary human T-cells
By activating the lactate transporter Slc5a12 on CD4 + T cells and inhibiting the expression of hexokinase 1 (HK1), lactate accumulation in synovial fluid (SF) reduced glycolytic flux in T cells and promotes FAS, which raises IL-17 production (152)
However, the same study concludes that a significant reduction (2.36.4) in titers of neutralising antibodies against other variants was observed [20]
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