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Pre-sleep timing is commonly used in rodent models to align with endogenous GH pulse rhythm

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The role of neuroprotectants in the therapeutic strategy to prevent or treat epilepsy is also discussed

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Individual components of the apoptotic machinery involved in regulation of ER stress-mediated cell death include Bax, Bak, Bim, or PUMA (p53 upregulated modulator of apoptosis), as well as the transcription factor CHOP (C/EBP homologous protein)-dependent pathway [89]

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