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This combined evidence suggests that phosphorylation of Tau is part of an immune response toward a broad range of pathogens or their toxins, similar to A, both of which are diverted from their normal roles in neuronal homeostasis

doi:10.1007/s00204-010-0579-8 Peraica M, Radic B, Lucic A, Pavlovic M

Yes, generally

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Cool-downs facilitate lactate clearance, lower heart rate recovery time, and minimise DOMS, promoting faster adaptation and adherence