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e-Cigarette use among youth in the United States, 2019

Bupropion Bupropion is a selective inhibitor of the neuronal reuptake of noradrenaline and dopamine that was initially approved for the treatment of depression, then for tobacco cessation in the United States in 1996 (Physicians Desk Reference, 2011)

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A 2021 risk assessment found that typical diacetyl exposure levels from e-cigarette use could result in hazard quotients up to 200300 times above safe limits, strongly suggesting a significant risk for irreversible small-airway fibrosis (bronchiolitis obliterans) among teen and adult vapers of diacetyl-containing flavors (11)

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