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Notably, the enzyme has been linked to obesity and type 2 diabetes (T2D)
Kraus D, Yang Q, Kong D, Banks AS, Zhang L, Rodgers JT, Pirinen E, Pulinilkunnil TC, Gong F, Wang YC, Cen Y, Sauve AA, Asara JM, Peroni OD, Monia BP, Bhanot S, Alhonen L, Puigserver P, Kahn BB. Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. Nature. 2014 Apr 10;508(7495):258-62. doi: 10.1038/nature13198. PMID: 24717514; PMCID: PMC4107212
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Chemical Information Chemical Name: 5-Amino-1-methylquinolinium Abbreviation: 5-Amino-1MQ CAS Number: 102365-69-1 Molecular Formula: C 10 H 10 N 2 Molecular Weight: 158.20 g/mol Form: Oral capsules, 50 mg Background & Research Findings what is 5-Amino-1MQ