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There is little risk from taking too much B12, however, high amounts may interact with certain medications

For research buyers, this can be an important signal of raw material quality and manufacturing care

Some researchers add an extra 0.1mL of bacteriostatic water to compensate, accepting a slightly lower concentration (3.23mg/mL instead of 3.33mg/mL) in exchange for recovering nearly all the peptide

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It can also be taken as a dietary supplement or administered through injections for individuals who have difficulty absorbing it from food

Whilst personal possession is not straightforwardly criminalised, its supply and sale are regulated under the Human Medicines Regulations 2012, and use without clinical oversight falls entirely outside regulated UK healthcare