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However, the capacity of sulfation is limited and competition between APAP and p -cresol will limit the detoxication of both by this route, increasing the likely formation of NAPQI as metabolism is pushed towards CYP2E1

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this channel appears to be positively modulated by intracellular lactate levels, forming a possible feedback loop for rapid lactate efflux [13]

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Individuals with a diabetes ICD code or use of glucose-modifying drug during the 8 year window were excluded

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