Serum B12 reference ranges vary between laboratories, but generally, levels below 148 pmol/L are considered deficient, whilst levels between 148258 pmol/L are regarded as borderline and may warrant further investigation or a trial of treatment, particularly if symptoms are present
Pharmacological Reviews, 59(2), 151184
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They serve different purposes but can be used together for enhanced results
And its not because of any magic its because these are natural substances that our bodies make and are familiar with, so thats what gives them this incredible safety profile. The FDA, however, has publicly stated that there is not enough evidence from human clinical trials on the safety or efficacy of these drugs
Translational Considerations and Safety NNMT has emerged as a systems-level regulator linking methylation capacity, NAD biology, and adipocyte energetics