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Start with tirzepatide monotherapy, titrate to therapeutic dose (12.515mg weekly), allow 1620 weeks to reach plateau, then reassess

A: Existing studies report good safety profiles, but long-term data in humans is limited

For patients with type 2 diabetes and painful neuropathy, results were similarly encouraging

Lipoic acid stimulates cAMP production in T lymphocytes and NK cells

Higher NAD is associated with SIRT1 activity, studied in relation to cellular repair, stress response, and aging pathways