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However, genetic variations, impaired hepatic processing, altered enterohepatic recycling, and gut microbiota imbalances can lead to bilirubin supersaturation, increasing the risk of gallstone formation

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Marrocco et al

The arginine-glycine-aspartic acid (RGD) sequence has been extensively applied in tumor-targeted therapy, mainly targeting v 3 receptors overexpressed on several tumor cells

FIGURE 1 2 Materials and methods 2.1 Materials Chitosan (76% deacetylated, and viscosity 122 cps, 1 wt% in 1% acetic acid), poly (ethylene oxide) (PEO, average Mv900,000), poly (D,L-lactide-co-glycolide) (PLGA, lactide: glycolide 50:50, Mw 45 kg/mol), QS, and LEV were purchased from Sigma-Aldrich (Germany)

Encapsulation in liposomes and NLCs improves the incorporation of AX into lipid bilayers due to the enhanced compatibility between the carrier matrix and biological phospholipids