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The Importance of Murine Models in Determining In Vivo Pharmacokinetics, Safety, and Efficacy in Antimalarial Drug Discovery

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Beyond their established role as energy substrates, SCFAs act as localized and systemic signaling molecules through G protein-coupled receptors (GPR41, GPR43, and GPR109A), thereby mediating bidirectional communication between the gastrointestinal tract and peripheral organs 165

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While glutathione is generally recognised as safe and well-tolerated, there are specific situations where professional guidance is mandatory