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This accumulation often results in distinct patterns of acylcarnitine profiles that are used diagnostically

It is also sensitive to serum due to expressing an unusual semi-rough form of lipopolysaccharide (LPS), in which the O-antigen is truncated after the first residue due to a nonsense mutation in the O-antigen polymerase gene 8

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However, a concomitant decrease in glutamine uptake within cancer cells has been demonstrated to meet the demand for glutamine by lymphocytes within the tumor mesenchyme