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Notably, hepatocytes within assembloids exhibited higher expression of periportal markers, including SAA1 , SAA2 , HAMP and APOA1 , whereas pericentral genes such as CYP2E1 , CYP3A4 and GLUL were downregulated relative to h-HepOrgs cultured alone (Fig

Both work below where topical skincare reaches, on the structural layer where firmness and texture actually live

The study only employed a single drug dose, overlooking dose-dependent investigations, which will also be addressed in subsequent research

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