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It inhibits the activation of the transcription factor NF-B, reducing the production of pro-inflammatory cytokines (IL-1, TNF-, IL-6) and inflammatory mediators (PGE2, NO)

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what are their toxicities, adverse effects or even their drug interactions

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Here we gave an oral drug once a day and saw healing to be greatly accelerated. Fracture healing is a significant health issue, especially for patients with diabetes, says Yang, the papers co-corresponding author