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Hijacking the host ubiquitin pathway: structural strategies of bacterial E3 ubiquitin ligases

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FLNA is composed of two subunits of 280 kDa each that self-assemble, each monomer possesses an actin-binding domain (ABD) at the N-terminus, that consists of two calponin homology domains, followed by 24 immunoglobulin (Ig)-like repeats of about 96 amino acid residues

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