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PMID: 32110280

A., Monnier, M., Waser, P

Dietary folate exists in polyglutamate form which must be converted into monoglutamate before absorption

The prescriber gets a workflow that doesnt require a fax machine or a phone call

For prescribers across functional medicine, integrative oncology, aesthetics, and neurology, choosing the right compounding partner is as clinically significant as the therapy itself

Its working mechanism is allosteric facilitation of HGF/c-Met signaling: Dihexa binds HGF with high affinity (reported K d ~65 pM in the original work) and is proposed to potentiate HGF dimerization and c-Met phosphorylation at subthreshold endogenous HGF concentrations