l carnitine and liver disease l-carnitine therapy in non-alcoholic steatohepatitis Nonalcoholic Fatty Gut-liver Axis: Role of Intestinal Microbiota and Therapeutic Mechanisms L-Carnitine Effect of L-Carnitine Supplementation on

Improving RA can be achieved by inhibiting ferroptosis and preventing excessive lipid peroxidation due to the accumulation of free iron ions in cells, thereby providing a potential target for RA treatment (Fig

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Studies have demonstrated that ALOX15 exacerbates I/R-induced brain injury [305] and ischemia-induced myocardial injury [306] by inducing PL-PUFA peroxidation and ferroptosis, suggesting the therapeutic potential of targeting ALOX15 for these I/R-induced tissue injuries

doi: 10.1186/s12931-023-02444-z 203 US National Library of Medicine

10.1002/tox.23123 5 AiJ.YangZ.LiuJ.ScholsH