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While it is a potent anti-inflammatory, scientific literature reveals that NAC can act as both a direct histamine liberator and a DAO (diamine oxidase) inhibitor

PubMed record Chang CH, et al

J.DueasM.PrietoM.Snchez-LpezE.ThomaleJ.et al (2017)

Targeting MST1 or its downstream effectors involved in ROS regulation might lead to novel strategies for modulating pyroptosis and its associated inflammatory consequences

It is suggested that this unique immunomodulatory profile contributes significantly to ketamines high clinical utility in acute pain management, perioperative, and critical care settings [174, 175]

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