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CRISPR-Cas9-mediated genome editing has successfully generated Brassica varieties with significantly increased glucoraphanin accumulation by modulating key genes in the pathway, including MYB28, AOP2, and BCAT4 (96, 107)

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Vukojevic et al., 2018) and those with bile duct induced liver cirrhosis and portal hypertension (Sever et al., 2019)

Inflammatory hypothesis Chronic inflammation, particularly in the brain, plays a significant role in the development and progression of various age-related diseases and neurodegenerative conditions

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