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It also carries its own risks of dependence and is a controlled substance

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Since the majority of clinical trials are either in phase I or II, further evaluation and testing is needed regarding long term toxicity and potential adverse effects associated with those drugs (248252)

As a result, there is a need for more efficient and streamlined synthetic methods to produce curcumin quickly and effectively (89)

It was double-blinded, randomized, and placebo-controlled [9]

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