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These included skin-colour changes and gastrointestinal problems

17 Currently, there is still a lack of consensus regarding the diagnosis or management of HAD, making it challenging to accurately delineate its prevalence and pathogenic mechanisms

Oligodendrocyte progenitor cells become regionally diverse and heterogeneous with age

Suggested starting points to discuss with your clinician Deficiency without malabsorption: 1,0002,000 mcg oral cyanocobalamin daily until normalized, then weekly or monthly maintenance per labs (AAFP)

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