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Shikonin inhibits the growth and N-acetylation of 2-aminofluorene in Helicobacter pylori from ulcer patients

A promising pathway for development of diagnosis and therapy I find it more fascinating that despite decades of ME/CFS research, and half a decade of #LongCovid research, that there are no validated, regulatory-approved biomarkers or FDA approved treatments for either condition

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Severa, M., Zhang, J., Giacomini, E., Rizzo, F., Etna, M

Medications affected by CYP3A4 inhibition CYP3A4 is perhaps the most prolific drug-metabolizing enzyme in the human body, handling roughly 30 to 40% of all pharmaceuticals