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Pre-incubation of RBL-2H3 cells with the guanylyl cyclase inhibitor ODQ (10 -6 M) for 30 min did not reverse the CSS-induced inhibition of degranulation

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A linear mixed-effects model for analysis of variance (ANOVA) was performed on the natural log-transformed pharmacokinetic parameters C max and AUC t following the morning product use session on each of Days 1, 2, 3, and 4

Food and Drug Administration

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