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This study was approved by the institutional review boards and conforms to the Helsinki Declaration

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Kisiel, MD Consultant, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota

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PatelBParetsSAkanaMKelloggGJansenMChangCet al

In mice, a high-Se diet increased TCR signaling in CD4 + T cells, increased IL-2 expression, shifted the Th1/Th2 balance toward a Th1 phenotype, higher levels of interferon- (IFN-) and CD40 ligand (60)