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Dexamethasone reduces acute tubular necrosis without improving renal failure To understand how these opposing mechanisms affect ferroptosis in complex pathophysiological settings, we next focused on acute kidney injury (AKI), which has been established as a standard model for ferroptotic cell death in vivo [9]

Enterobactin inhibits microbiota-dependent activation of AhR to promote bacterial sepsis in mice

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More importantly, oral administration of these compounds leads to their accumulation in the brain, heart, muscle and liver mitochondria (Ross et al., 2005)

TMT labeling Each sample was labeled by 3 l of the corresponding 6-plex TMT tag (20 g/l) at room temperature for 1 h

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