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The combination lacks specific safety and efficacy data and should be investigated with appropriate caution in controlled research settings

The pH-dependent drug uptake mechanism functions similarly to the pH-dependent transmembrane redistribution of weak bases

10.1038/nrclinonc.2013.125 31 DeSantisC

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doi: 10.1007/s00424-020-02352-x 128 RyszJ.FranczykB.awiskiJ.OlszewskiR.Ciakowska-RyszA.Gluba-BrzzkaA

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