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This design resulted in one group of children who had topical glutathione and oral DMSA challenge followed by continued administration of DMSA and a second group of participants who underwent a single round of DMSA challenge without topical glutathione and who subsequently did not receive any further chelation

Similarly, in cisplatin-induced renal injury, microRNA (miR)-4835p (37) promotes the expression of GPX3, thereby mitigating oxidative stress and exerting a protective effect on renal injury (38)

These effects can further reduce neuron damage and apoptosis