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It has been shown that KPT-9274 can promote apoptosis and induce DNA damage in vitro, 312 and significantly reduces tumor proliferation and survival in xenograft models in different tumors, such as pancreatic cancer, 309 pancreatic neuroendocrine tumors, 313 triple-negative breast cancer 311 , and leukemia

Past researchers used the analog PMS of 5MPCA to characterize the specific antifungal machinery of 5MPCA and found that phenazines could covalently bind soluble proteins in C

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Detoxification This is one of the primary biological roles of glutathione in the body