The tamoxifen-induced mitochondrial stress has been attributed to its inhibition of complex I and III of the mitochondria electron transport complexes (mETC) [46,47,48] and a consequent increase of intracellular ROS in both ER- + and ER-- cells [49]
As discussed, the quality varies wildly based on whether the product is liposomal or standard
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Specifically, the Patient Health Questionnaire (PHQ-9) score for depression dropped significantly from 13.03 to 9.84, and the Fibromyalgia Impact Questionnaire (FIQ) score dropped from 49.55 to 43.03