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Wilson's disease: People with this rare inherited disease store too much copper in their brain and liver

We do not know the optimal human dosing, long-term safety profile in humans, or whether animal results translate directly to human outcomes

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However, the VPA model was specifically selected for its ability to: (1) mimic the gut microbiota dysbiosis observed in ASD patients [45], which genetic models often fail to reproduce [44]

It is not known whether the mtDNA mutations in autistic patients are a cause or effect of ASD