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doi: 10.3390/nu11092073 29

Neuron 109 , 24852498.e5 (2021)

L., Sheen, J

Last Updated: March 27, 2026 Sources of NADPH The reduced form of nicotinamide adenine dinucleotide phosphate (NADPH) is critical to numerous reductive biosynthetic processes such as fatty acid synthesis, cholesterol synthesis, bile acid synthesis, steroid hormone synthesis, and deoxynucleotide synthesis

NTS (240) were transferred to U-bottom 96 well assay plates containing 200 l of M199 medium supplemented with 5.5 mM D-glucose, penicillin-streptomycin and 5% heat inactivated fetal bovine serum and incubated at 37 C in a 5% CO 2 incubator overnight

Some of these key functions, namely antioxidant defense, redox signaling, storage of cysteine via the -glutamyl cycle, regulation of growth and death are described in more detail below