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Moreover, gene amplification is a way that in chronic myelogenous leukemia (CML) lead to over expression of the Bcr-Abl protein as a mechanism of acquired imatinib resistance [137]

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Key exclusion criteria included diabetes, previous or planned surgical treatment for obesity, use of medications that promote weight loss or gain, or a weight change of more than 5 kg in the three months before screening

Journal of Biomaterials Science, Polymer Edition, 19(8), 969988

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