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They have different mechanisms and different evidence bases

MHRA guidance Medicines and Healthcare products Regulatory Agency

While these effects are generally manageable, they represent more pronounced GI side effects than observed with AOD-9604

Capogrosso P, Jensen CFS, Rastrelli G, et al

However, desiccants represent a secondary measure and cannot substitute for appropriate temperature control

Results from a 2017 study show an association with consuming high-dose B6 and B12 vitamin supplements over 10 years with an increase in lung cancer risk in men, especially smokers (Brasky, 2017)