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Once in the CNS parenchyma, CD4+ T-cells induce inflammatory response from both macrophages and the resident CNS glia: mainly astrocytes and microglia
De AK, Muthiyan R, Mondal S, Mahanta N, Bhattacharya D, Ponraj P, Muniswamy K, Kundu A, Kundu MS, Sunder J, et al
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After stopping a CYP3A4 inhibitor, as the effects of the inhibitor decline, the Hydrocodone Bitartrate and Acetaminophen Tablets plasma concentration will decrease [see CLINICAL PHARMACOLOGY], resulting in decreased opioid efficacy or a withdrawal syndrome in patients who had developed physical dependence to Hydrocodone Bitartrate and Acetaminophen Tablets
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