Cellular organelles, such as mitochondria and the endoplasmic reticulum, produce ROS during metabolic processes, which stimulate the generation of free radicals through various pathways
Additionally, molecular docking analysis of BPA and BPA-o-quinone (BPAQ) against selected antioxidant targets, and HPLCMS-revealed AEFEVL compounds against Keap-1 and IKK targets, followed by ADMET analysis, was conducted
Cognitive deterioration and Alzheimer's disease Mitochondrial dysfunction and oxidative stress are thought to contribute to the onset and/or progression of several neurodegenerative diseases, especially Alzheimer's disease (AD) (102)
Panelli S, Epis S, Cococcioni L, Perini M, Paroni M, Bandi C, Drago L, Zuccotti GV
The body adapts
Ammar et al